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    VPA is absorbed rapidly so if timing of ingestion is unknown this may not be helpful.See the end of this leaflet for a complete list of ingredients in What should I tell my healthcare provider before taking Depakote or Depakene? Before you take Depakote or Depakene, tell your healthcare provider if you: have a genetic liver problem caused by a mitochondrial disorder e.

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    Advertising and sponsorship policyAdvertising and sponsorship opportunities A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo, "Mayo Clinic, "MayoClinic.The contents of the ampoule are for single use only.

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    Talk to your doctor if you re concerned about how valproic acid may affect your fertility.J Neurosci.

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    Before you take Valproic Acid Capsules, tell your healthcare provider if you: have a genetic liver problem caused by a mitochondrial disorder e.Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug ReferenceDisclosure: Received salary from Medscape for employment. for: Medscape.

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    2012 Aug 20.Valproic Acid Capsules are contraindicated in patients known to have mitochondrial disorders caused by POLG mutations and children valproic acid iv loading dose two years of age who are clinically suspected of having a mitochondrial disorder POLG-related disorders should be suspected in patients with a family history or suggestive symptoms of a POLG-related disorder, including but not valproic acid iv loading dose to unexplained encephalopathy, refractory epilepsy focal, myoclonic status epilepticus at presentation, developmental delays, psychomotor regression, axonal sensorimotor neuropathy, myopathy cerebellar ataxia, ophthalmoplegia, or complicated migraine with occipital aura.

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