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Spectral domain-OCT displays bilateral and severe inner segment thioridazine generic name zone loss in the temporal perifovea e and f Hydroxychloroquine Plaquenil Wide angle fundus autofluorescence illustrates the progression of hydroxychloroquine thioridazine generic name toxicity over time despite discontinuation of the drug in both eyes in the more eccentric pericentral distribution a h Note the pathologic alterations displayed with spectral domain-OCT throughout the follow-up which include progressive outer retinal perifoveal thinning and loss of the ellipsoid zone band i p Thioridazine Mellaril is an anti-psychotic phenothiazine derivative that was first clinically used in 1959.kin: Dermatitis and skin eruptions of the urticarial type have been observed infrequently.
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The early fundus changes often progress despite discontinuation of the drug.to 1. times the risk of death in placebo-treated patients.
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It was therefore an unanticipated finding after breaking the code at the end of the study to find that as many discontinuations of the study occurred with the original medication and dosage as with drug withdrawal.
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