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|Pronunciation||/ s ɪ t ə ˈ ɡ l ɪ p t ɪ n / ( listen )|
|Trade names||Januvia, Tesavel, Xelevia, others|
|License data||EU EMA: by INN, US FDA: Sitagliptin|
|Pregnancy category||AU: B3 US: B (No risk in non-human studies)|
|Routes of administration||By mouth|
|ATC code||A10BH01 ( WHO )|
|Legal status||AU: S4 (Prescription only) UK: POM (Prescription only) US: ℞-only|
|Metabolism||Liver (CYP3A4- and CYP2C8-mediated)|
|Elimination half-life||8 to 14 h |
|Excretion||Kidney (80%) |
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|Januvia alternative name||sitagliptina, sitagliptine, sitagliptinum, tesavel, xelevia|
|Bestellers||10 tablets in a package x 100 mg|
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SITAGLIPTIN ( Januvia ®) 100mg tablet. Class of drugs: Oral anti-diabetic agent. Indication: Treatment of diabetes mellitus, Type 2. Manufacturer: Merck Frosst ...:
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It was also found to be active for a very short time in the blood. This is because it is broken down quickly by an enzyme called dipeptidyl peptidase 4, or DPP-4.If heart failure develops, evaluate and manage according to current standards of care and consider discontinuation of NESINA.
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