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Clinical data
Pronunciation/ ˌ d aɪ f ɛ n ˈ h aɪ d r ə m iː n /
Trade namesBenadryl, Unisom, Sominex, others
Pregnancy categoryAU: A US: B (No risk in non-human studies)
Dependence liabilityVery low
Routes of administrationBy mouth, intramuscular injection, intravenous, topical, rectal
ATC codeD04AA32 ( WHO ) D04AA33 ( WHO ), R06AA02 ( WHO )
Legal status
Legal statusAU: S2 (Pharmacy only) US: OTC
Pharmacokinetic data
Bioavailability40–60% [2]
Protein binding98–99%
MetabolismLiver (CYP2D6 (80%), CYP3A4 (10%)) [1]
Elimination half-lifeRange: 2.4–13.5 hrs [3] [2] [4]
ExcretionUrine: 94% [5] Feces: 6% [5]

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Do not give other cough-and-cold benadryl dose 40 lbs that might contain the same or similar ingredients see also Drug Interactions section Ask the doctor or pharmacist about other ways to relieve cough and cold symptoms such as drinking enough fluids, using a humidifier or saline nose drops/spray Take this medication by mouth as directed by your doctor.t this point, my PCP is okay with my decision.

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Om provides accurate and independent information on more than 24, 00 benadryl dose 40 lbs drugs, over-the-counter medicines and natural products.enadryl is an over-the-counter medicine that can be given to dogs. Diphenhydramine, the most common active ingredient, is an H1 antagonist, which means it helps to prevent the uptake of histamine a type of substance responsible for allergic reactions by receptors in the body.

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Diphenhydramine overdose during pregnancy: lessons from the past. m J Obstet Gynecol.Other medications may also contain aspirin, diphenhydramine, phenylpropanolamine, or other similar drugs, and you may accidentally take too much and harm yourself.

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