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Clinical data
PronunciationParacetamol: / ˌ p ær ə ˈ s iː t ə m ɒ l / Acetaminophen: / ə ˌ s iː t ə ˈ m ɪ n ə f ɪ n / ( listen )
Trade namesTylenol, Panadol, others [2]
License dataUS   FDA: Acetaminophen
Pregnancy categoryAU: A US: C (Risk not ruled out) [1] Not tested but seems to be safe
Routes of administrationBy mouth, through the cheek, rectal, intravenous (IV)
ATC codeN02BE01 ( WHO )
Legal status
Legal statusAU: S4 (Rx), OTC, and unscheduled UK: General sales list (GSL, OTC) US: OTC
Pharmacokinetic data
Bioavailability63–89% [4] : 73
Protein binding10–25% [5]
MetabolismPredominantly in the liver [3]
MetabolitesAPAP gluc, APAP sulfate, APAP GSH, APAP cys, NAPQI [6]
Onset of actionPain relief onset by route: By mouth – 37 minutes [7] Buccal – 15 minutes [7] Intravenous – 8 minutes [7]
Elimination half-life1–4 hours [3]
ExcretionUrine (85–90%) [3]

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En casos raros, acetaminophen puede causar una reacci n severa de la piel que puede ser acetaminophen for abdominal pain, que es dolo neurobion forte. Esto puede ocurrir a n si usted ha tomado acetaminophen anteriormente y no tuvo ninguna reacci n. Deje de tomar esta medicina y llame a su m dico de inmediato si usted tiene enrojecimiento de la piel o sarpullido que se extiende y acetaminophen for abdominal pain ampollas y descamaci n.

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Elimination of acetaminophen is principally by liver metabolism conjugation and subsequent renal excretion of metabolites. Acetaminophen is primarily metabolized in the acetaminophen dosage 1 year old by first-order kinetics and involves three principal separate pathways: conjugation with glucuronide; conjugation with sulfate; and oxidation via the cytochrome P450-dependent, mixed-function oxidase enzyme pathway to form a reactive intermediate metabolite, which conjugates with glutathione and is then further metabolized to form cysteine and mercapturic acid conjugates.Market Research World.

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Prompt medical attention is critical for adults as well as for children even if you do not notice any signs or symptoms. TAMPER EVIDENT: DO NOT USE IF OUTER PACKAGE IS OPENED OR BLISTER IS TORN OR BROKEN corn starch, crospovidone, flavor, magnesium stearate, maltodextrin, microcrystalline acetaminophen dosage 1 year old, polyethylene glycol, polyvinyl alcohol, povidone, silica gel, silicon dioxide, sodium starch glycolate, stearic acid, sucralose, talc, titanium dioxide ACETAMINOPHEN / PAIN RELIEVER / FEVER REDUCERGUAIFENESIN / EXPECTORANTPHENYLEPHRINE HCl / NASAL DECONGESTANT Relieves headache, fever, stuffy nose, sinus pressure, chest congestion mucus TAMPER EVIDENT: DO NOT USE IF PACKAGE ISOPENED OR IF BLISTER UNIT IS TORN, BROKENOR SHOWS ANY SIGNS OF TAMPERING This product is not manufactured ordistributed by McNeil ConsumerHealthcare, acetaminophen dosage 1 year old of the registeredtrademark Tylenol Cold + HeadCongestion Severe.If someone has overdosed and has serious symptoms such as passing out or trouble breathing, give them naloxone if available, then call 911.

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Primary attention should be given to the reestablishment of adequate respiratory exchange through provision of a patent airway and the institution of assisted or controlled ventilation. Supportive measures including oxygen, intravenous fluids, and vasopressors should be employed in the management of circulatory shock and pulmonary edema accompanying overdose as indicated.Store as directed on the package label.

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Intuitively, strategies that improve parent education and promote parent physician communication should be effective.Before using this medication, women of childbearing age should talk with their docto s about the risks and benefits.

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These factors may affect how you should use this medication.There were no major adverse events occurring in more than 1% of participants with paracetamol plus metoclopramide in either study. Eight studies reported on withdrawals due to adverse events.

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